Generation Scotland: Donor DNA Databank; A control DNA resource
نویسندگان
چکیده
منابع مشابه
Challenges to Design and Develop of DNA Aptamers for Protein Targets. I. Optimization of Asymmetric PCR for Generation of a Single Stranded DNA Library
Aptamers, or single stranded oligonucleotides, are produced by systematic evolution of ligands by exponential enrichment, abbreviated as SELEX. In the amplification and regeneration step of SELEX technique, dsDNA is conversed to ssDNA. Asymmetric PCR is one of the methods used for the generation of ssDNA. The purpose of this study was to design a random DNA library for selection of aptamers wit...
متن کاملChallenges to Design and Develop of DNA Aptamers for Protein Targets. I. Optimization of Asymmetric PCR for Generation of a Single Stranded DNA Library
Aptamers, or single stranded oligonucleotides, are produced by systematic evolution of ligands by exponential enrichment, abbreviated as SELEX. In the amplification and regeneration step of SELEX technique, dsDNA is conversed to ssDNA. Asymmetric PCR is one of the methods used for the generation of ssDNA. The purpose of this study was to design a random DNA library for selection of aptamers wit...
متن کاملA convenient method to generate methylated and un-methylated control DNA in methylation studies
Methylated and un-methylated control DNA is an important part of DNA methylation studies. Although human and mouse DNA methylation control sets are commercially available, in case of methylation studies on other species such as animals, plants, and bacteria, control sets need to be prepared. In this paper a simple method of generating methylated and un-methylated control DNA is described. Whole...
متن کاملOGG1 DNA Repair Gene Polymorphism As a Biomarker of Oxidative and Genotoxic DNA Damage
Background: Single nucleotide polymorphisms in 8-oxoguanine DNA glycosylase-1 (OGG1) gene modulates DNA repair capacity and functions as one of the first lines of protective mechanisms against 8-hydroxy-2’-deoxyguanosine (8-OHdG) mutagenicity. OGG1-Cys326 gene polymorphism may decrease DNA repair function, causing oxidative stress due to higher oxidative DNA damage. The main purpose of this stu...
متن کاملکامپیوترهای DNA
مبنای کارکرد کامپیوترهای امروزی، کاربرد کدهای دوتایی «صفر» و «یک» همچنین روشن و خاموش شدن مدار ریزتراشه است که عملکرد کامپیوتر را از ساده‌ترین مانند جمع و تفریق تا پیچیده‌ترین آنها مانند معادلات تفارقی دربرمی‌گیرد. از آنجایی که مولکول DNA دارای کد است می‌توان از آن به عنوان یک کامپیوتر مولکولی که از چهار مبنای قابل پیش‌بینی و در ارتباط با هم تشکیل شده استفاده کرد به عنوان یک ماده آلی بر مبنای س...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMC Medical Genetics
سال: 2010
ISSN: 1471-2350
DOI: 10.1186/1471-2350-11-166